This home was constructed for Newton DePauw, son of the late Washington C. DePauw. The house was immediately sold to the recently-appointed pastor of Trinity ME Church, the Reverend Henry J. Talbott, in October 1889 for $2,500. Reverend Talbott had been pastor at Centenary ME Church prior to his taking the pastorate at Trinity.

In May 1894, Reverend Talbott sold the house to Charles W. Inman for $2,800 and left Trinity Church in September of that same year. Charles was a grocer early in his career before becoming president of Col. E.V. Knight’s New Albany Veneering Co., located at East 13^th Street and the Ohio River.

The Inman family remained at this location until about 1902, when their new, handsome Queen Anne style home was finished next door at 1322 East Spring Street.

Other families that have owned the Talbott-Inman House over the years have included: Joshua Lemmon, James Stewart and Osborne Reilly families.