Constructed in 1870, this served as the rectory for Holy Trinity Catholic Church, which stood on the lot to the east. The church was destroyed by fire in December 1975, but its ruins remain as a monument. The photos below, from the collection of the Indiana Room, New Albany-Floyd County Public Library, show the interior of Holy Trinity circa 1965 and the exterior circa 1905.

The rectory recently was completely rehabilitated by St. Elizabeth Regional Maternity Center as their offices.