This was originally a four-story structure, which has housed numerous businesses since its construction in 1855. The earliest tenant was John R. Nunemacher, who had his City Bookstore and publishing company here. In the 20th century, the following companies occupied the building: Rhodes-Burford Co., furniture and carpet; The Tribune Co., New Albany Tribune, New Albany Ledger and Tribune; and Karl Fenger & Son Hardware. Later, Reisz Furniture Company's 'Pilgrim Shop' sold Early American-style furniture and reproductions of Colonial pieces out of this storefront.

The drawing below shows the building circa 1890, at its original height. The building likely took on its current configuration following the 1937 flood; at that time, two othe four-story buildings along Main Street were damaged and subsequently reduced to two stories.