This stately brick home, which combines elements of both the Greek Revival and Federal styles, was constructed between 1848-53 by master builder and architect Isaac P. Smith as his own residence. This home marked the beginning of the residential portion of Upper High Street, as East Main Street was known at the time, home to many of the city's elite and most prosperous citizens. Isaac Smith was also the designer of several other homes in the district, including the Joshua Bragdon House (517 E. Main), the Montgomery-Cannon House (518 E. Main), the Sloan-Bicknell-Paris House (600 E. Main) and the James and Angelina Collins House (917 E. Main), among many other private and public buildings in New Albany.